Larbi is interested in the microbiological changes that may trigger diseases in human and animals, with a focus on the interaction between host and microbiome. As a postdoctoral fellow in the Croitoru lab, he is exploring the factors that may trigger Crohn's disease in genetically susceptible individuals. This is made possible by mining the outstanding GEM project database, which includes data on first degree relatives (FDRs) of Crohn's disease patients. Currently, his primary focus is on studying the interaction between FDRs genetics and their microbiome using a large bioinformatics and statistical toolset.